Single-cell RNA-Seq revealed profound immune alteration in the peripheral blood of patients with bacterial infection

Objectives: Bacterial infection remains one of the greatest threats to human health.However, how human hosts respond to bacterial infection has not been thoroughly understood.Better understanding of this response will improve human health.Methods: Here, we conducted an investigation on host response to bacterial infection using unperturbed clinical

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Standardisation of Clinical Assessment, Management and Follow-Up of Acute Hospitalised Exacerbation of COPD: A Europe-Wide Consensus

Sanjay Ramakrishnan,1– 3 Wim Janssens,4 Pierre-Regis Burgel,5 Marco Contoli,6 Frits ME Franssen,7 Neil J Greening,8 Timm Greulich,9 Iwein Gyselinck,4 Andreas Halner,1 Arturo Huerta,10 Rebecca L Morgan,11 Jennifer K Quint,12 Lowie EGW Vanfleteren,13 Kristina Vermeersch,4 Henrik Watz,14 Mona Bafadhel1 1Respiratory Medicine Unit, Nuffield Depart

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Actigraphy-based sleep estimation in adolescents and adults: a comparison with polysomnography using two scoring algorithms

Mirja Quante,1–3 Emily R Kaplan,2 Michael Cailler,2 Michael Rueschman,2 Rui Wang,2–5 Jia Weng,2 Elsie M Taveras,3,5,6 Susan Redline2,3,7 1Department of Neonatology, University of Tuebingen, Tuebingen, Germany; 2Division of Sleep and Circadian Disorders, Departments of Medicine and Lip Balm Neurology, Brigham and Women’s Hospital,

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